• Joint Strength*
• Liver Detoxification*
• Mood and Brain Function*
•Enteric-Coated Pharmaceutical Grade SAMe
•Central biochemical building block
•#1 SAMe Product in Dollars Sales†
•68-80% Active S,S Form
•Made Naturally By Fermentation
† #1 in Dollar Sales, according to SPINS, a market research and consulting firm for the Natural Product Industry (SPINScan Natural, 52 Weeks Ending 11/29/08)
What does SAM-e 400 do?
Jarrow FORMULAS® pharmaceutical grade, stabilized SAM-e 400 provides a full 400 mg SAM-e (net yield) from 800 mg of SAM-e tosylate disulfate. SAM-e 400 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product.
Contains More of the Active S,S Form
Found in all living cells, SAM-e is a metabolite of methionine (an essential amino acid). SAM-e is a chiral molecule and consists of two forms: (S,S) SAM-e and (R,S) SAM-e. The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive. Jarrow FORMULAS® SAM-e is made naturally by microbiological fermentation and then specially processed without solvents to preserve 68-80% (S,S) SAM-e, the highest active level available.
SAM-e has been clinically shown to have the following benefits:
SAM-e supports the production of healthy connective tissue through transulfuration. In this process, critical components of connective tissue, including glucosamine and the chondroitin sulfates, are sulfated by SAM-e metabolites.*
SAM-e methylation reactions are involved in the synthesis of neurotransmitters such as L-DOPA, dopamine and related hormones, serotonin, epinephrine and phosphatidylcholine (a component of lecithin).*
Methylation of DNA appears to be important in the suppression of errors in DNA replication. Demethylation of DNA is considered a contributor to the aging process. Proper methylation through substances such as SAM-e positively influences longevity.*
SAM-e metabolism supports the synthesis of glutathione (GSH) and glutathione-dependent enzymes (glutathione peroxidase and glutathione-S-transferase), which are substances important for liver function.*
PRODUCT OF ITALY
Keep out of the reach of children.
Take 1 tablet per day on an empty stomach, or as directed by your qualified health care consultant.
WARNING: Individuals using prescribed medications such as antidepressants, including Selective Serotonin Re-Uptake Inhibitors (SSRIs) and MAO Inhibitors should consult a physician before using. Individuals with Parkinson's disease, bi-polar disorder or manic depression should not use SAM-e.
Jarrow FORMULAS® SAM-e 400 is foil blister-packed to maximize stability and safety. DO NOT use if outer seal of blister pack is broken.
Full Potency 400 mg SAM-e is derived from 800 mg of SAM-e tosylate disulfate.
For best results, use with Jarrow FORMULAS® JarroSil®, the biologically Activated Silicon®.
Store in a cool, dry place.
Cellulose, silicon dioxide, glyceryl behenate, magnesium stearate (vegetable source), enteric coating (methacrylate copolymers), titanium dioxide, magnesium silicate, triethylcitrate, riboflavin, glycerol palmitostearate, medium chain triglycerides, carboxymethyl starch sodium salt and mannitol.
Suitable for vegetarians/vegans.
No wheat, no gluten, no soybeans, no dairy, no egg, no fish/shellfish, no peanuts/tree nuts.
This product complies with the proposed USP Monograph for SAM-e.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.